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Other Names:

Alfacalcidol: 1-alpha-hydroxycholecalciferol, 1-alpha-hydroxycholécalciférol, 1 alpha (OH)D3

Calcifediol: 25-HCC, 25-hydroxycholecalciferol, 25-hydroxycholécalciferol , 25-hydroxyvitamin D3, 25-hydroxyvitamine D3, 25-OHCC, 25-OHD3, Calci

See All Names Alfacalcidol: 1-alpha-hydroxycholecalciferol, 1-alpha-hydroxycholécalciférol, 1 alpha (OH)D3

Calcifediol: 25-HCC, 25-hydroxycholecalciferol, 25-hydroxycholécalciferol , 25-hydroxyvitamin D3, 25-hydroxyvitamine D3, 25-OHCC, 25-OHD3, Calcifédiol

Calcipotriene : Calcipotriène, Calcipotriol

Calcitriol: 1,25-DHCC, 1,25-dihydroxycholecalciferol, 1,25-dihydroxycholécalciférol, 1,25-dihydroxyvitamin D3, 1,25-dihydroxyvitamine D3, 1,25-diOHC, 1,25(0H)2D3

Cholecalciferol: 7-déhydrocholestérol Activé, Activated 7-dehydrocholesterol, Cholécalciférol, Colecalciferol, Colécalciférol, Vitamin D3

Dihydrotachysterol: DHT, Dihydrotachystérol, dihydrotachysterol 2, dichysterol, Vitamine D3

Ergocalciferol: Activated Ergosterol, Calciferol, Ergocalciférol, Ergocalciferolum, Ergostérol Activé, Ergostérol Irradié, Irradiated Ergosterol, Viosterol, Viostérol, Vitamin D2, Vitamine D2

Paricalcitol: 19-nor-1,25-dihydroxyvitamin D2, 19-nor-1,25-dihydroxyvitamine D2, Paracalcin

Fat-Soluble Vitamin, Vitamina D, Vitamine D, Vitamine Liposoluble, Vitamine Soluble dans les Graisses

VITAMIN D Overview Information

Vitamin D is a vitamin It can be found in small amounts in a few foods, including fatty fish such as herring, mackerel, sardines and tuna To make vitamin D more available, it is added to dairy products, juices, and cereals that are then said to be “fortified with vitamin D” But most vitamin D – 80% to 90% of what the body gets – is obtained through exposure to sunlight Vitamin D can also be made in the laboratory as medicine

How does it work?

Vitamin D is required for the regulation of the minerals calcium and phosphorus found in the body It also plays an important role in maintaining proper bone structure

VITAMIN D Uses & Effectiveness

Effective for:

Likely Effective for:

  • Bone loss in people taking drugs called corticosteroids Taking vitamin D (calcifediol, cholecalciferol, calcitriol, or alfacalcidol) by mouth prevents bone loss in people taking drugs called corticosteroids Taking vitamin D alone or with calcium seems to improve bone density in people with existing bone loss caused by using corticosteroids
  • Preventing falls in older people Researchers have observed that people who do not have enough vitamin D tend to fall more often than people who do Taking a vitamin D supplement seems to reduce the risk of falling by up to 22% Higher doses of vitamin D are more effective than lower doses One study found that taking 800 IU of vitamin D reduced the risk of falling, but lower doses did not
  • Also, vitamin D, in combination with calcium, but not calcium alone, may prevent falls by decreasing body sway and blood pressure Taking vitamin D plus calcium seems to prevent falls more significantly in women than men and in older people living in hospitals or residential care facilities than those living in community dwellings
  • Osteoporosis (weak bones) Taking a specific form of vitamin D called cholecalciferol (vitamin D3) along with calcium seems to help prevent bone loss and bone breaks

Possibly Effective for:

Possibly Ineffective for:

  • Breast cancer Evidence on the effects of vitamin D on breast cancer risk is inconsistent The best evidence comes from a large study called the Women’s Health Initiative, which found that taking 400 IU of vitamin D and 1000 mg of calcium per day does not lower the chance of getting breast cancer when taken by postmenopausal women However, the possibility remains that high doses of vitamin D might lower breast cancer risk in younger women
  • Muscle strength Taking vitamin D (cholecalciferol) by mouth daily does not increase muscle strength or improve physicical performance in healthy older men who are not vitamin D deficient
  • Bone loss in people with kidney transplants Taking vitamin D (calcitriol) daily together with calcium carbonate does not decrease bone loss in people with kidney transplants
  • Tuberculosis Vitamin D does not appear to help cure tuberculosis infections

Insufficient Evidence for:

VITAMIN D Side Effects & Safety

Vitamin D is LIKELY SAFE when taken by mouth or given as a shot into the muscle in recommended amounts Most people do not commonly experience side effects with vitamin D, unless too much is taken Some side effects of taking too much vitamin D include weakness, fatigue, sleepiness, headache, loss of appetite, dry mouth, metallic taste, nausea, vomiting, and others

Special Precautions & Warnings:

VITAMIN D Interactions

Moderate Interaction Be cautious with this combination

  • Aluminum interacts with VITAMIN D

Aluminum is found in most antacids Vitamin D can increase how much aluminum the body absorbs This interaction might be a problem for people with kidney disease Take vitamin D two hours before, or four hours after antacids

Calcipotriene is a drug that is similar to vitamin D Taking vitamin D along with calcipotriene (Dovonex) might increase the effects and side effects of calcipotriene (Dovonex) Avoid taking vitamin D supplements if you are taking calcipotriene (Dovonex)

Vitamin D helps your body absorb calcium Calcium can affect the heart Digoxin (Lanoxin) is used to help your heart beat stronger Taking vitamin D along with digoxin (Lanoxin) might increase the effects of digoxin (Lanoxin) and lead to an irregular heartbeat If you are taking digoxin (Lanoxin), talk to your doctor before taking vitamin D supplements

Vitamin D helps your body absorb calcium Calcium can affect your heart Diltiazem (Cardizem, Dilacor, Tiazac) can also affect your heart Taking large amounts of vitamin D along with diltiazem (Cardizem, Dilacor, Tiazac) might decrease the effectiveness of diltiazem

Vitamin D helps your body absorb calcium Calcium can affect the heart Verapamil (Calan, Covera, Isoptin, Verelan) can also affect the heart Do not take large amounts of vitamin D if you are taking verapamil (Calan, Covera, Isoptin, Verelan)

Vitamin D helps your body absorb calcium Some "water pills" increase the amount of calcium in the body Taking large amounts of vitamin D along with some "water pills" might cause to be too much calcium in the body This could cause serious side effects including kidney problems

Minor Interaction Be watchful with this combination

  • Cimetidine (Tagamet) interacts with VITAMIN D

The body changes vitamin D into a form that it can use Cimetidine might decrease how well the body changes vitamin D This might decrease how well vitamin D works But this interaction probably isn't important for most people

Heparin slows blood clotting and can increase the risk of breaking a bone when used for a long period of time People taking these medications should eat a diet rich in calcium and vitamin D

Some medications called low molecular weight heparins can increase the risk of breaking a bone when used for a long periods of time People taking these medications should eat a diet rich in calcium and vitamin D

VITAMIN D Dosing

The following doses have been studied in scientific research:

See 334 Reviews for this Treatment - OR -

Related to VITAMIN D

Conditions & Treatments Related to VITAMIN D

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version Information from this source is evidence-based and objective, and without commercial influence For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version © Therapeutic Research Faculty 2009

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